Conversion Of Embryonic Form To Adult Forms Of N

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Conversion Of Embryonic Form To Adult Forms Of N

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  • These outcomes indicate that in cultured neural tissue, the E form of N-CAM is not processed into A forms however is progressively degraded and replaced by newly synthesized A types.
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Data that’s obtainable consists of informati… The neural cell adhesion molecule (N-CAM) inhibits proliferation in major cultures of rat astrocytes. The mechanism of binding of neural cell adhesion molecules.

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The rate of E-to-A conversion and the proportions of the different A types synthesized in vitro were just like these observed for the tissues in vivo at comparable occasions. These outcomes counsel that the publish translational processing in vitro was just like that in vivo. The information have been consistent with the possibility that the rise in synthesis of A forms occurred either in cells that had beforehand synthesized E varieties or in a definite population of cells that already synthesized A forms. In pulse-chase experiments, the E form of N-CAM that was synthesized through the first day after explantation continued as E kind for a number of days, at times when newly synthesized N-CAM was predominantly in A forms.

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